-
- May 19, 2012: Orlando Hudson - Cleared Waivers and Became a Free Agent
- May 19, 2012: Matt Palmer - Purchased From Minors
- May 19, 2012: Cory Luebke - Transferred to 60-Day DL ((Left elbow soreness))
- May 19, 2012: Nick Vincent - Sent to Minors
- May 18, 2012: Mark Kotsay - Placed on 15-Day DL ((Lower back strain))
- May 18, 2012: Blake Tekotte - Called Up from Minors
- May 18, 2012: Nick Vincent - Sent to Minors
- May 17, 2012: Tim Stauffer - Placed on 15-Day DL ((Right elbow sprain))
- May 17, 2012: Nick Vincent - Called Up from Minors
- May 17, 2012: James Darnell - Placed on 15-Day DL ((Left shoulder subluxation))
- May 16, 2012: Orlando Hudson - Designated for Assignment
- May 16, 2012: Alexi Amarista - Called Up from Minors
- May 16, 2012: Jason Bartlett - Placed on 15-Day DL ((Strained right knee))
- May 16, 2012: Everth Cabrera - Called Up from Minors
- May 16, 2012: Eric Stults - Acquired Off Waivers From (Chi. White Sox)
- May 15, 2012: Carlos Quentin - Recalled From Minors (Rehab Assignment)
- May 13, 2012: Logan Forsythe - Sent to Minors (For Rehabilitation)
- May 13, 2012: Tim Stauffer - Removed From 15-Day DL ((Strained right elbow))
- May 12, 2012: Josh Spence - Sent to Minors
- May 10, 2012: James Darnell - Called Up from Minors
- May 10, 2012: Joe Wieland - Placed on 15-Day DL ((Strained right elbow))
- May 7, 2012: Anthony Reyes - Signed to a Minor League Contract
- May 7, 2012: Alex Hinshaw - Purchased From Minors
- May 7, 2012: Blake Tekotte - Sent to Minors
- May 7, 2012: Kip Wells - Signed to a Minor League Contract
- May 7, 2012: Micah Owings - Transferred to 60-Day DL ((Strained right forearm))
- May 6, 2012: Daniel Stange - Signed to a Minor League Contract
- May 4, 2012: Miles Mikolas - Purchased From Minors
- May 4, 2012: Logan Forsythe - Transferred to 60-Day DL ((Left foot fracture - out 6-8 weeks))
- May 4, 2012: Huston Street - Placed on 15-Day DL ((Right lat strain))
- May 3, 2012: Brad Brach - Called Up from Minors
- May 2, 2012: Alexi Amarista - Sent to Minors
- May 1, 2012: Cory Luebke - Placed on 15-Day DL ((Left elbow soreness))
- May 1, 2012: Jeff Suppan - Purchased From Minors
- May 1, 2012: Kyle Blanks - Transferred to 60-Day DL ((Left shoulder surgery - out for season))
- Apr 30, 2012: Carlos Quentin - Sent to Minors (For Rehabilitation)
- Apr 28, 2012: Tim Stauffer - Sent to Minors (For Rehabilitation)
- Apr 27, 2012: Blake Tekotte - Called Up from Minors
- Apr 27, 2012: Jeremy Hermida - Placed on 15-Day DL ((Right hip flexor sprain))
- Apr 25, 2012: Micah Owings - Placed on 15-Day DL ((Strained right forearm))
- Apr 25, 2012: Dale Thayer - Purchased From Minors
- Apr 25, 2012: Dustin Moseley - Transferred to 60-Day DL ((Right shoulder surgery - out for season))
- Apr 15, 2012: Mark Kotsay - Removed From 15-Day DL ((Right calf strain))
- Apr 15, 2012: Brad Brach - Sent to Minors
- Apr 13, 2012: Kyle Blanks - Placed on 15-Day DL ((Left shoulder surgery - out for season))
- Apr 13, 2012: Joe Wieland - Purchased From Minors
- Apr 10, 2012: Mark Kotsay - Sent to Minors (For Rehabilitation)
- Apr 7, 2012: Dustin Moseley - Placed on 15-Day DL ((Right shoulder surgery - out for season))
- Apr 7, 2012: Josh Spence - Called Up from Minors
- Apr 6, 2012: Brian Tallet - Traded From (Pittsburgh (for future considerations))
- Apr 4, 2012: Erik Hamren - Called Up from Minors (- Not to Report)
- Apr 4, 2012: Brad Brach - Called Up from Minors
- Apr 4, 2012: Tim Stauffer - Placed on 15-Day DL ((Strained right elbow))
- Apr 3, 2012: Jeremy Hermida - Purchased From Minors
- Apr 2, 2012: Carlos Quentin - Placed on 15-Day DL ((Right knee surgery - out 4-6 weeks))
- Apr 2, 2012: Mark Kotsay - Placed on 15-Day DL ((Right calf strain))
- Apr 2, 2012: Everth Cabrera - Sent to Minors
- Apr 2, 2012: Jeremy Hermida - Purchased From Minors
- Apr 2, 2012: Brad Brach - Sent to Minors
- Mar 31, 2012: Erik Hamren - Designated for Assignment
- Mar 31, 2012: James Darnell - Sent to Minors
- Mar 29, 2012: Cory Luebke - Signed (( 2012-2015; Opt 2016-2017)(four-year contract extension))
- Mar 25, 2012: Logan Forsythe - Placed on 15-Day DL ((Left foot fracture - out 6-8 weeks))
- Mar 19, 2012: Nick Hundley - Signed (( 2013-2014; Opt 2015)(two-year extension))
- Mar 15, 2012: Josh Spence - Sent to Minors
- Mar 15, 2012: Nick Vincent - Sent to Minors
- Mar 14, 2012: Blake Tekotte - Sent to Minors
- Mar 14, 2012: Erik Hamren - Sent to Minors
- Mar 6, 2012: Dennis Tankersley - Signed to a Minor League Contract
- Mar 2, 2012: Cameron Maybin - Signed (( 2012-2016; Opt 2017)(five-year extension))
- Feb 7, 2012: Jeff Suppan - Signed to a Minor League Contract
- Feb 2, 2012: Micah Owings - Signed as Free Agent (( 2012)(one-year contract))
- Jan 31, 2012: Micah Owings - Signed as Free Agent (( 2012)(one-year contract))
- Jan 30, 2012: Dustin Moseley - Signed (( 2012)(avoids arbitration))
- Jan 22, 2012: Clayton Richard - Signed (( 2012)(avoids arbitration))
- Jan 19, 2012: David Eckstein - Retired
- Jan 16, 2012: Nick Hundley - Signed (( 2012)(avoids arbitration))
- Jan 16, 2012: Chase Headley - Signed (( 2012)(avoids arbitration))
- Jan 16, 2012: Tim Stauffer - Signed (( 2012)(avoids arbitration))
- Jan 16, 2012: Joe Thatcher - Signed (( 2012)(avoids arbitration))
- Jan 16, 2012: Edinson Volquez - Signed (( 2012)(avoids arbitration))
- Jan 16, 2012: Luke Gregerson - Signed (( 2012)(avoids arbitration))
- Jan 16, 2012: Carlos Quentin - Signed (( 2012)(avoids arbitration))
- Jan 16, 2012: Will Venable - Signed (( 2012)(avoids arbitration))
- Jan 16, 2012: John Baker - Signed (( 2012)(avoids arbitration))
- Jan 5, 2012: Andrew Cashner - Traded From (Chi. Cubs (for 1B Anthony Rizzo, four-player deal))
- Jan 2, 2012: Brad Davis - Signed to a Minor League Contract
- Dec 30, 2011: Carlos Quentin - Traded From (Chi. White Sox (for Ps Simon Castro and Pedro Hernandez))
- Dec 18, 2011: Jeremy Hermida - Signed to a Minor League Contract
- Dec 16, 2011: Yasmani Grandal - Traded From (Cincinnati (for RHP Mat Latos, five-player deal))
- Dec 16, 2011: Luis Martinez - Designated for Assignment
- Dec 16, 2011: Yonder Alonso - Traded From (Cincinnati (for RHP Mat Latos, five-player deal))
- Dec 16, 2011: Edinson Volquez - Traded From (Cincinnati (for RHP Mat Latos, five-player deal))
- Dec 14, 2011: Eric Patterson - Released
- Dec 11, 2011: Jeremy Hermida - Not Offered Contract and Became Free Agent ((non-tendered))
- Dec 11, 2011: Chris Denorfia - Signed (( 2012)(avoids arbitration))
- Dec 6, 2011: Huston Street - Traded From (Colorado (with cash for LHP Nick Schmidt))
- Dec 6, 2011: Jeremy Hermida - Designated for Assignment
- Dec 5, 2011: Dale Thayer - Signed to a Minor League Contract
- Nov 30, 2011: Matt Palmer - Signed to a Minor League Contract
- Nov 30, 2011: Alex Hinshaw - Signed to a Minor League Contract
- Nov 21, 2011: John Baker - Traded From (Miami (for LHP Wade LeBlanc))
- Nov 17, 2011: Nick Vincent - Purchased From Minors
- Nov 17, 2011: Alberto Gonzalez - Cleared Waivers and Became a Free Agent
- Nov 16, 2011: Mark Kotsay - Signed as Free Agent (( 2012)(one-year contract))
- Nov 15, 2011: Alberto Gonzalez - Released
- Oct 29, 2011: Aaron Harang - Declared Free Agency ((mutual option declined))
- Oct 29, 2011: Brad Hawpe - Declared Free Agency ((mutual option declined))
- Oct 29, 2011: Heath Bell - Declared Free Agency
- Oct 29, 2011: Chad Qualls - Declared Free Agency ((team option declined))
- Oct 27, 2011: Dustin Moseley - Removed From 60-Day DL ((Strained left shoulder))
- Oct 27, 2011: Clayton Richard - Removed From 60-Day DL ((Strained left shoulder))
- Oct 24, 2011: Rob Johnson - Outrighted to Minors
- Oct 19, 2011: Jeff Fulchino - Refused Minor League Assignment - Free Agent
- Oct 10, 2011: Kyle Phillips - Refused Minor League Assignment - Free Agent
- Sep 28, 2011: Pat Neshek - Refused Minor League Assignment - Free Agent
- Sep 27, 2011: Blake Tekotte - Called Up from Minors (- Not to Report)
- Sep 27, 2011: Everth Cabrera - Called Up from Minors (- Not to Report)
- Sep 27, 2011: Cedric Hunter - Called Up from Minors (- Not to Report)
- Sep 27, 2011: Simon Castro - Called Up from Minors (- Not to Report)
- Sep 18, 2011: Chase Headley - Removed From 15-Day DL ((Fractured left pinkie finger))
- Sep 5, 2011: Pat Neshek - Outrighted to Minors
- Sep 5, 2011: Erik Hamren - Called Up from Minors
- Sep 4, 2011: Chris Denorfia - Removed From 15-Day DL ((Strained right hamstring))
- Sep 3, 2011: James Darnell - Called Up from Minors
- Sep 3, 2011: Anthony Rizzo - Called Up from Minors
- Sep 1, 2011: Andrew Carpenter - Acquired Off Waivers From (Philadelphia)
- Sep 1, 2011: Luis Martinez - Called Up from Minors
- Sep 1, 2011: Evan Scribner - Called Up from Minors
- Sep 1, 2011: Kyle Phillips - Outrighted to Minors
- Aug 31, 2011: Jeff Fulchino - Acquired Off Waivers From (Houston)
- Aug 31, 2011: Pat Neshek - Designated for Assignment
- Aug 30, 2011: Dustin Moseley - Transferred to 60-Day DL ((Strained left shoulder))
- Aug 30, 2011: Blake Tekotte - Sent to Minors
- Aug 30, 2011: Kyle Phillips - Designated for Assignment
- Aug 30, 2011: Jeremy Hermida - Acquired Off Waivers From (Cincinnati)
- Aug 30, 2011: Brad Brach - Purchased From Minors
- Aug 30, 2011: Chris Denorfia - Sent to Minors (For Rehabilitation)
- Aug 29, 2011: Erik Hamren - Sent to Minors
- Aug 29, 2011: Blake Tekotte - Called Up from Minors
- Aug 25, 2011: Clayton Richard - Transferred to 60-Day DL ((Strained left shoulder))
- Aug 25, 2011: Andy Parrino - Purchased From Minors
- Aug 23, 2011: Pat Neshek - Sent to Minors
- Aug 23, 2011: James Darnell - Sent to Minors
- Aug 21, 2011: Chris Denorfia - Recalled From Minors (Rehab Assignment)
- Aug 20, 2011: Pat Neshek - Designated for Assignment
- Aug 20, 2011: Ernesto Frieri - Removed From 15-Day DL ((Back injury))
- Aug 19, 2011: Ernesto Frieri - Recalled From Minors (Rehab Assignment)
- Aug 13, 2011: Chris Denorfia - Sent to Minors (For Rehabilitation)
- Aug 13, 2011: Pat Neshek - Called Up from Minors
- Aug 13, 2011: Blake Tekotte - Sent to Minors
- Aug 12, 2011: Ernesto Frieri - Sent to Minors (For Rehabilitation)
- Aug 11, 2011: Nick Hundley - Removed From 15-Day DL ((Strained right elbow))
- Aug 11, 2011: Luis Martinez - Sent to Minors
- Aug 9, 2011: Pedro Feliz - Signed to a Minor League Contract
- Aug 7, 2011: James Darnell - Purchased From Minors
- Aug 7, 2011: Wade LeBlanc - Called Up from Minors
- Aug 7, 2011: Chase Headley - Placed on 15-Day DL ((Fractured left pinkie finger))
- Aug 7, 2011: Brad Hawpe - Transferred to 60-Day DL ((Left elbow surgery - out for season))
- Aug 7, 2011: Ernesto Frieri - Placed on 15-Day DL ((Back injury))
- Aug 5, 2011: Blake Tekotte - Called Up from Minors
- Aug 5, 2011: Chris Denorfia - Placed on 15-Day DL ((Strained right hamstring))
- Aug 4, 2011: Joe Thatcher - Removed From 60-Day DL ((Strained left shoulder))
- Aug 2, 2011: Blake Tekotte - Sent to Minors
- Aug 2, 2011: Drew Macias - Signed to a Minor League Contract
- Aug 1, 2011: Nick Hundley - Sent to Minors (For Rehabilitation)
- Jul 31, 2011: Wade LeBlanc - Sent to Minors
- Jul 31, 2011: Aaron Cunningham - Called Up from Minors
- Jul 31, 2011: Blake Tekotte - Called Up from Minors
- Jul 30, 2011: Dustin Moseley - Placed on 15-Day DL ((Strained left shoulder))
- Jul 30, 2011: Wade LeBlanc - Called Up from Minors
- Jul 30, 2011: Erik Hamren - Purchased From Minors
- Jul 28, 2011: Pat Neshek - Sent to Minors
- Jul 28, 2011: Ernesto Frieri - Reinstated from Paternity Leave List
- Jul 25, 2011: Pat Neshek - Called Up from Minors
- Jul 25, 2011: Luis Martinez - Called Up from Minors
- Jul 25, 2011: Ernesto Frieri - Placed on Paternity Leave List
- Jul 25, 2011: Kyle Phillips - Sent to Minors
- Jul 21, 2011: Mike Baxter - Removed From 60-Day DL ((Torn ligament, left thumb))
- Jul 21, 2011: Kyle Blanks - Called Up from Minors
- Jul 20, 2011: Anthony Rizzo - Sent to Minors
- Jul 19, 2011: Jason Bartlett - Reinstated from Paternity Leave List
- Jul 19, 2011: Everth Cabrera - Sent to Minors
- Jul 16, 2011: John Van Benschoten - Signed to a Minor League Contract
- Jul 16, 2011: Joe Thatcher - Sent to Minors (For Rehabilitation)
- Jul 16, 2011: Jason Bartlett - Placed on Paternity Leave List
- Jul 16, 2011: Everth Cabrera - Called Up from Minors
- Jul 15, 2011: Luis Martinez - Sent to Minors
- Jul 15, 2011: Logan Forsythe - Called Up from Minors
- Jul 8, 2011: Aaron Harang - Removed From 15-Day DL ((Right foot contusion))
- Jul 7, 2011: Pat Neshek - Sent to Minors
- Jul 7, 2011: Nick Hundley - Placed on 15-Day DL ((Strained right elbow))
- Jul 7, 2011: Luis Martinez - Called Up from Minors
- Jul 6, 2011: Mike Baxter - Sent to Minors (For Rehabilitation)
- Jul 4, 2011: Clayton Richard - Placed on 15-Day DL ((Strained left shoulder))
- Jul 4, 2011: Luke Gregerson - Removed From 15-Day DL ((Strained left oblique))
- Jul 3, 2011: Aaron Harang - Sent to Minors (For Rehabilitation)
- Jun 30, 2011: Luke Gregerson - Sent to Minors (For Rehabilitation)
- Jun 25, 2011: Anthony Bass - Called Up from Minors
- Jun 25, 2011: Evan Scribner - Sent to Minors
- Jun 22, 2011: Jorge Cantu - Cleared Waivers and Became a Free Agent
- Jun 20, 2011: Brad Hawpe - Placed on 15-Day DL ((Left elbow surgery - out for season))
- Jun 20, 2011: Josh Spence - Purchased From Minors
- Jun 20, 2011: Luis Durango - Designated for Assignment
- Jun 20, 2011: Kyle Phillips - Called Up from Minors
- Jun 20, 2011: Jorge Cantu - Released
- Jun 20, 2011: Wade LeBlanc - Sent to Minors
- Jun 18, 2011: Logan Forsythe - Sent to Minors
- Jun 18, 2011: Orlando Hudson - Removed From 15-Day DL ((Left groin strain))
- Jun 15, 2011: Aaron Poreda - Outrighted to Minors
- Jun 15, 2011: Jesus Guzman - Purchased From Minors
- Jun 15, 2011: Jorge Cantu - Designated for Assignment
- Jun 15, 2011: Eric Patterson - Outrighted to Minors
- Jun 13, 2011: Orlando Hudson - Sent to Minors (For Rehabilitation)
- Jun 13, 2011: Wade LeBlanc - Called Up from Minors
- Jun 12, 2011: Anthony Bass - Sent to Minors
- Jun 12, 2011: Cameron Maybin - Removed From 15-Day DL ((Paterllar tendinitis in right knee))
- Jun 12, 2011: Aaron Poreda - Designated for Assignment
- Jun 12, 2011: Aaron Harang - Placed on 15-Day DL ((Right foot contusion))
- Jun 11, 2011: Kyle Phillips - Sent to Minors
- Jun 9, 2011: Cameron Maybin - Sent to Minors (For Rehabilitation)
- Jun 8, 2011: Will Venable - Called Up from Minors
- Jun 8, 2011: Evan Scribner - Called Up from Minors
- Jun 8, 2011: Luke Gregerson - Placed on 15-Day DL ((Strained left oblique))
- Jun 8, 2011: Anthony Rizzo - Purchased From Minors
- Jun 8, 2011: Aaron Cunningham - Sent to Minors
- Jun 8, 2011: Eric Patterson - Designated for Assignment
- Jun 7, 2011: Nick Hundley - Removed From 15-Day DL ((Strained right oblique))
- Jun 7, 2011: Blake Tekotte - Sent to Minors
- Jun 3, 2011: Nick Hundley - Sent to Minors (For Rehabilitation)
- Jun 1, 2011: Jarrett Hoffpauir - Outrighted to Minors
- May 31, 2011: Aaron Cunningham - Called Up from Minors
- May 31, 2011: Cameron Maybin - Placed on 15-Day DL ((Paterllar tendinitis in right knee))
- May 28, 2011: Steve Tolleson - Traded From (Oakland (for cash considerations))
- May 26, 2011: Orlando Hudson - Placed on 15-Day DL ((Left groin strain))
- May 26, 2011: Logan Forsythe - Called Up from Minors
- May 25, 2011: Samuel Deduno - Outrighted to Minors
- May 23, 2011: Alex Cintron - Retired
- May 22, 2011: Will Venable - Sent to Minors
- May 22, 2011: Samuel Deduno - Designated for Assignment
- May 22, 2011: Blake Tekotte - Purchased From Minors
- May 18, 2011: Orlando Hudson - Removed From 15-Day DL ((Strained right hamstring))
- May 18, 2011: Evan Scribner - Sent to Minors
- May 16, 2011: Logan Forsythe - Sent to Minors
- May 16, 2011: Pat Neshek - Called Up from Minors
- May 14, 2011: Jarrett Hoffpauir - Sent to Minors (For Rehabilitation)
- May 14, 2011: Orlando Hudson - Sent to Minors (For Rehabilitation)
- May 5, 2011: Kyle Phillips - Purchased From Minors
- May 5, 2011: Jarrett Hoffpauir - Transferred to 60-Day DL ((Strained right quadriceps))
- May 5, 2011: Nick Hundley - Placed on 15-Day DL ((Strained right oblique))
- May 3, 2011: Orlando Hudson - Placed on 15-Day DL ((Strained right hamstring))
- May 3, 2011: Joe Thatcher - Transferred to 60-Day DL ((Strained left shoulder))
- May 3, 2011: Logan Forsythe - Purchased From Minors
- May 2, 2011: Alex Cintron - Signed to a Minor League Contract
- Apr 25, 2011: Kyle Blanks - Recalled From Minors (Rehab Assignment)
- Apr 24, 2011: Evan Scribner - Called Up from Minors
- Apr 23, 2011: Wade LeBlanc - Sent to Minors
- Apr 22, 2011: Pat Neshek - Sent to Minors
- Apr 13, 2011: Kyle Blanks - Sent to Minors (For Rehabilitation)
- Apr 10, 2011: Mat Latos - Removed From 15-Day DL ((Strained right shoulder))
- Apr 9, 2011: Samuel Deduno - Sent to Minors
- Apr 9, 2011: Eric Patterson - Removed From 15-Day DL ((Strained left hamstring))
- Apr 9, 2011: Wade LeBlanc - Sent to Minors
- Apr 8, 2011: Cedric Hunter - Sent to Minors
- Apr 8, 2011: Eric Patterson - Recalled From Minors (Rehab Assignment)
- Apr 6, 2011: Eric Patterson - Sent to Minors (For Rehabilitation)
- Mar 29, 2011: Kyle Blanks - Placed on 15-Day DL ((Recovery from right elbow surgery))
- Mar 28, 2011: Jarrett Hoffpauir - Placed on 15-Day DL ((Strained right quadriceps))
- Mar 28, 2011: Samuel Deduno - Called Up from Minors
- Mar 28, 2011: Eddie Kunz - Traded From (NY Mets (for 1B Allan Dykstra))
- Mar 28, 2011: Mat Latos - Placed on 15-Day DL ((Strained right shoulder))
- Mar 28, 2011: Joe Thatcher - Placed on 15-Day DL ((Strained left shoulder))
- Mar 27, 2011: Wade LeBlanc - Sent to Minors
- Mar 27, 2011: Eric Patterson - Placed on 15-Day DL ((Strained left hamstring))
- Mar 27, 2011: Everth Cabrera - Sent to Minors
- Mar 27, 2011: Mike Baxter - Placed on 60-Day DL ((Torn ligament, left thumb))
- Mar 27, 2011: Alberto Gonzalez - Traded From (Washington (for RHP Erik Davis & cash considerations))
- Mar 27, 2011: Oscar Salazar - Released
- Mar 27, 2011: Aaron Cunningham - Sent to Minors
- Mar 27, 2011: Cedric Hunter - Called Up from Minors
- Mar 24, 2011: Kevin Frandsen - Released
- Mar 19, 2011: Samuel Deduno - Sent to Minors
- Mar 19, 2011: Luis Durango - Sent to Minors
- Mar 19, 2011: Pat Neshek - Acquired Off Waivers From (Minnesota)
- Mar 14, 2011: Cedric Hunter - Sent to Minors
- Mar 13, 2011: George Kontos - Drafted Player Returned to Minors
- Mar 10, 2011: Simon Castro - Sent to Minors
- Mar 10, 2011: Luis Martinez - Sent to Minors
- Mar 10, 2011: Aaron Poreda - Sent to Minors
- Mar 10, 2011: Evan Scribner - Sent to Minors
- Mar 6, 2011: Gregg Zaun - Retired
- Mar 4, 2011: Jon Leicester - Signed to a Minor League Contract
- Feb 15, 2011: Geoff Geary - Signed to a Minor League Contract
- Feb 9, 2011: Randy Flores - Signed to a Minor League Contract
- Feb 6, 2011: Oscar Salazar - Outrighted to Minors
- Feb 2, 2011: David Newhan - Signed to a Minor League Contract
- Feb 2, 2011: Bobby Kielty - Signed to a Minor League Contract
- Feb 2, 2011: Matt Riley - Signed to a Minor League Contract
- Jan 30, 2011: Jorge Cantu - Signed as Free Agent (( 2011)(one-year contract))
- Jan 30, 2011: Oscar Salazar - Designated for Assignment
- Jan 27, 2011: Samuel Deduno - Acquired Off Waivers From (Colorado)
- Jan 25, 2011: Greg Burke - Signed to a Minor League Contract
- Jan 19, 2011: Chad Qualls - Signed as Free Agent (( 2011; Opt 2012)(one-year contract))
- Jan 17, 2011: Heath Bell - Signed (( 2011)(avoids arbitration))
- Jan 17, 2011: Tim Stauffer - Signed (( 2011)(avoids arbitration))
- Jan 17, 2011: Chase Headley - Signed (( 2011)(avoids arbitration))
- Jan 17, 2011: Mike Adams - Signed (( 2011)(avoids arbitration))
- Jan 17, 2011: Ryan Ludwick - Signed (( 2011)(avoids arbitration))
- Jan 17, 2011: Gregg Zaun - Signed to a Minor League Contract
- Jan 9, 2011: Jason Bartlett - Signed (( 2011-2012; Opt 2013)(two-year contract, avoids arbitration))
- Jan 5, 2011: Kevin Frandsen - Signed to a Minor League Contract
- Jan 5, 2011: Radhames Liz - Cleared Waivers and Became a Free Agent ((signed by LG Twins (KBO)))
- Jan 4, 2011: Guillermo Quiroz - Signed to a Minor League Contract
- Jan 3, 2011: Radhames Liz - Released
- Jan 2, 2011: Brad Hawpe - Signed as Free Agent (( 2011; Opt 2012)(one-year contract))
- Dec 20, 2010: Orlando Hudson - Signed as Free Agent (( 2011-2012; Opt 2013)(two-year contract))
- Dec 20, 2010: Rob Johnson - Traded From (Seattle (for player to be named))
- Dec 16, 2010: Jason Bartlett - Traded From (Tampa Bay (for RHP Adam Russell, six-player deal))
- Dec 15, 2010: Eric Patterson - Traded From (Boston (to complete 12/5 Adrian Gonzalez deal))
- Dec 12, 2010: Dustin Moseley - Signed as Free Agent (( 2011)(one-year contract))
- Dec 9, 2010: Gregorio Petit - Signed to a Minor League Contract ((voided due to offseason injury))
- Dec 8, 2010: George Kontos - Drafted Via Rule 5 from Minors
- Dec 7, 2010: Aaron Harang - Signed as Free Agent (( 2011; Opt 2012)(one-year contract))
- Dec 2, 2010: Luis Perdomo - Signed to a Minor League Contract
- Dec 1, 2010: Tony Gwynn Jr. - Not Offered Contract and Became Free Agent ((non-tendered))
- Dec 1, 2010: Luis Perdomo - Not Offered Contract and Became Free Agent ((non-tendered))
- Dec 1, 2010: Scott Hairston - Not Offered Contract and Became Free Agent ((non-tendered))
- Dec 1, 2010: Matt Antonelli - Not Offered Contract and Became Free Agent ((non-tendered))
- Nov 30, 2010: Chris Denorfia - Signed (( 2011)(avoids arbitration))
- Nov 22, 2010: Jon Garland - Offered arbitration under Article XXB (3)
- Nov 22, 2010: Yorvit Torrealba - Offered arbitration under Article XXB (3)
- Nov 22, 2010: Kevin Correia - Offered arbitration under Article XXB (3)
- Nov 19, 2010: Jesus Guzman - Signed to a Minor League Contract
- Nov 17, 2010: Brandon Gomes - Purchased From Minors
- Nov 17, 2010: Simon Castro - Purchased From Minors
- Nov 17, 2010: Cedric Hunter - Purchased From Minors
- Nov 17, 2010: Evan Scribner - Purchased From Minors
- Nov 17, 2010: Luis Martinez - Purchased From Minors
- Nov 12, 2010: Cameron Maybin - Traded From (Florida (for RHPs Edward Mujica and Ryan Webb))
- Nov 2, 2010: Matt Antonelli - Removed From 60-Day DL ((Broken hamate bone, left hand))
- Nov 2, 2010: Kyle Blanks - Removed From 60-Day DL ((Right elbow surgery - out for season))
- Nov 2, 2010: Chris Young - Declared Free Agency ((team option declined))
- Nov 1, 2010: Adrian Gonzalez - Signed (( 2011)(team option exercised))
- Nov 1, 2010: Jon Garland - Declared Free Agency ((mutual option declined))
- Oct 31, 2010: Matt Stairs - Declared Free Agency
- Oct 31, 2010: David Eckstein - Declared Free Agency
- Oct 31, 2010: Miguel Tejada - Declared Free Agency
- Oct 31, 2010: Yorvit Torrealba - Declared Free Agency ((mutual option declined))
- Oct 31, 2010: Jerry Hairston Jr. - Declared Free Agency
- Oct 31, 2010: Kevin Correia - Declared Free Agency
- Oct 19, 2010: Erik Hamren - Signed to a Minor League Contract
- Oct 7, 2010: Chris Stewart - Outrighted to Minors
- Oct 5, 2010: Jarrett Hoffpauir - Acquired Off Waivers From (Toronto)
- Oct 5, 2010: Chris Stewart - Designated for Assignment
- Sep 30, 2010: Aaron Poreda - Called Up from Minors (- Not to Report)
- Sep 30, 2010: Lance Zawadzki - Called Up from Minors (- Not to Report)
- Sep 30, 2010: Radhames Liz - Called Up from Minors (- Not to Report)
- Sep 30, 2010: Luis Perdomo - Called Up from Minors (- Not to Report)
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