Zetterberg went for an MRI following Sunday’s 4-2 win over the Ottawa Senators after suffering from back spasms.
In 30 games with the Red Wings this season, the skilled Swede has a team high 19 assists, 30 points and plus-12 rating.
This is a huge blow to a Detroit team that is already without Pavel Datsyuk, who’s on the sidelines recovering from a concussion. Holland said he believes Datsyuk is getting better, but there’s no specific timetable for his return.
The Red Wings, who recalled centre Cory Emmerton from the Grand Rapids Griffins of the American Hockey League Tuesday, currently sit in fourth place in the Eastern Conference and are riding a four-game win streak.