Chimera scored the game’s first goal at 12:02 of the opening period.
Predators captain Shea Weber had the puck inside the Nashville blue line, but his pass attempt was intercepted by Wilson. He carried the puck into the right faceoff circle and sent a pass in front to Chimera, who tipped it by goalie Pekka Rinne.
Washington is 27-1-0 when scoring first this season.
The Predators carried the majority of the play in the first, outshooting the Capitals 14-6, but Holtby was sharp throughout.
He denied Cody Bass' backhand attempt from in close at 2:11 and then made back-to-back saves on Weber and Ryan Johansen on a power play 2 minutes later. Holtby stopped Weber's slap shot from the left point, then stuck his leg out and kicked away Johansen's rebound attempt at what appeared to be an open net.
Wilson made it 2-0 at 4:55 of the second.
Following another Nashville turnover, Johansson carried the puck on the right side and sent a cross-ice pass toward Wilson, who beat Rinne with a one-timer from inside the left circle.
Rinne finished with 18 saves.
Forsberg halved the Washington lead at 14:42 of the second with a wrist shot from the left faceoff dot that beat Holtby high to the far side.
Washington regained a two-goal lead in the third on Williams' 17th goal when Evgeny Kuznetsov sent a pass from the left dot to Williams in the low slot for the tap-in.
Kuznetsov has assists in three consecutive games.
Johansson scored at 8:03 of the third and Josi answered at 9:49.
Forsberg drew Nashville within one at the 12-minute mark when he scored his second of the night.
Ovechkin scored an empty-net goal on the power play with a minute remaining to seal the Washington victory.
NOTES: Washington LW Andre Burakovsky had an assist, extending his point streak to eight games. ... Kuznetsov's assist was his 100th NHL point. ... Forsberg has three goals and two assists in his last two games against his former team.