Lundqvist got his 30th victory of the season, joining Martin Brodeur and Patrick Roy as the only goalies in NHL history to have at least 30 wins in 10 different seasons.
Lundqvist also passed Mike Richter as the team’s all-time regular season saves leader with save on Vladimir Tarasenko’s wrist shot late in the first period.
Troy Brouwer scored for the Blues.
Fittingly, Lundqvist's save on Scottie Upshall's breakaway led to the game-winning goal. Seconds after the pad save, Oscar Lindberg found Kreider in the slot to make it 2-1 Rangers at 4:18 of the third period.
Glass put the Rangers up 1-0 with 6:46 to go in the first after tipping a shot by Dan Girardi from the point over Jake Allen's right shoulder. It was Glass' second goal of the season and first in 29 games.
Blues forward Jori Lehtera was hit in the face with the puck with just over a minute left in the first and didn't return.
Brouwer's power play goal for the Blues with a little more than 5 1/2 minutes remaining in the second tied the game at 1-1. It came 55 seconds after Girardi received a double-minor for high-sticking Tarasenko.
Brouwer's goal extended the Blues' power-play scoring streak at home to six games, the longest streak for St. Louis since a six-game span from Dec. 31, 2005, to Jan. 26, 2006.
Lundqvist kept the game tied with several tough saves, including gloving Colton Parayko's wrist shot in the second period and stopping Dmitrij Jaskin on a point-blank chance early in the third.
Allen made 22 saves in his first start since suffering a lower-body injury on Jan. 8.
The Rangers now have a four-game points streak against the Blues (3-0-1) and 14 of the last 17 meetings between the teams have been decided by two goals or fewer.
NOTES: Blues F Ryan Reaves served the first of a three-game suspension for a hit on San Jose's Matt Tennyson on Monday. ... Blues placed G Brian Elliott (lower body) on long-term injured reserve Tuesday and recalled G Pheonix Copley and F Ty Rattie from Chicago of the AHL. ... Rangers assigned D Brady Skjei to Hartford of the AHL on Wednesday. ... D Marc Staal (lower body) and D Ryan McDonagh (jaw contusion/neck spasms) returned to the Rangers' lineup.