Ryne Stanek opened the game, striking out three in two perfect innings, and was followed by Austin Pruitt (2 2/3 innings), Jonny Venters (one-third of an inning), Chaz Roe (1 1/3 innings), Jose Alvarado (1 2/3 innings) and Sergio Romo (one inning).
Pruitt (2-3) allowed four hits and a run but picked up the win. Romo allowed the other hit but locked down his second save.
Ramos put the Rays up 2-0 with his two-run drive off Jaime Garcia (2-5) in the third.
Garcia gave up four runs, four hits, four walks and struck out four in five-plus innings. The left-hander is 1-4 in seven road starts, allowing 28 earned runs over 31 1/3 innings.
Garcia departed after C.J Cron walked and went to third on Willy Adames’ double to start the sixth. Pinch-hitter Joey Wendle and Mallex Smith both had run-scoring singles off Joe Biagini that made it 4-1.
Toronto had runners on second and third with no outs in the fifth but scored just once on Devon Travis’ grounder off Pruitt.
Blue Jays: 3B Josh Donaldson (left calf tightness) remains day to day. … RHP Marcus Stroman (shoulder) will make a rehab start Wednesday night with Class A Dunedin.
Rays: CF Kevin Kiermaier (right thumb torn ligament) went 2 for 4 with a walk in his first minor league rehab game with Class A Charlotte and hopes to be back June 22. … OF Johnny Field (sore knee) was available off the bench.
HOUSE OF HORRORS
The Blue Jays have dropped the first two games in the three-game set and are 73-105 at Tropicana Field. It’s the most losses at any road ballpark since 1998, the Rays’ inaugural season.
REACHING A DECADE
Romo reached 10 years of major league service time Monday and was given a postgame celebration by his teammates. "A pretty awesome day," Romo said.
Tampa Bay will have another bullpen game Wednesday against Blue Jays LHP J.A. Happ (8-3).