Cano appeared to hurt the leg while running to first base when he grounded out in the third following J.D. Davis’ two-out double.
The 36-year-old Cano is batting .241 with three homers and 13 RBIs. The eight-time All-Star, was acquired by New York from Seattle in December.
Twice last weekend Cano failed to run out grounders in Miami, both of them resulting in double plays.