The Buffalo Bills will try to rebound from their second worst loss in franchise history when they return home on Sunday to battle the Los Angeles Chargers as 7-point underdogs on the NFL Week 2 odds at sportsbooks monitored by OddsShark.com.
The Bills are coming off a crushing 47-3 defeat in Baltimore as 7.5-point underdogs last weekend, a defeat topped only by a 56-10 loss to the New England Patriots in 2007. Last week’s loss also continues a low-scoring trend that has seen Buffalo average a meagre 12.5 points per game in eight outings ahead of Sunday afternoon’s matchup at New Era Field.
Despite their offensive struggles, hope remains that the Bills can regain the touch that earned them five against-the-spread wins in their final seven contests last season. Buffalo has also posted a reliable 14-6 SU record in its past 20 home dates, and plays host to a Chargers squad that has scored more than 17 points just once during a 3-3 SU run on the road.
The Detroit Lions will also be looking to bury the memory of a brutal Week 1 loss as they visit the San Francisco 49ers as 5.5-point underdogs, while the Chicago Bears try to bounce back from a second-half collapse in Sunday night’s 24-23 loss to Green Bay as they return home to host the Seattle Seahawks as 3-point favourites.
The Lions proved to be no match for the youngest quarterback to start a season opener since the AFL and NFL merged in 1970. Sam Darnold exceeded early expectations by leading the New York Jets to a 48-17 win over Detroit as 7-point underdogs, which also represents the most points that the Lions have surrendered in a game since 2009.
Things get no easier for the Lions in San Francisco, where they have failed to record a win in 22 visits since 1950. The Niners return home after opening the season with a 24-16 loss in Minnesota as 6-point underdogs, but have won three of four at home to end an 11-game SU slide on home turf, according to the OddsShark NFL Database.
The win over San Francisco has lifted the Vikings to a short +800 on the Super Bowl 53 odds. Minnesota has also taken four of five from the Packers, capped by a 16-0 victory in Green Bay as 8.5-point chalk last December.
Elsewhere, the defending Super Bowl champion Philadelphia Eagles travel to Tampa Bay to battle the surprising Buccaneers as 3-point chalk, while the Jets return home to face the division-rival Miami Dolphins as 3-point favourites.