Lowry initially suffered the injury late in the second quarter when he collided with the Bucks' D.J. Augustin on defence near the baseline, landing awkwardly and twisting his ankle. He went back to the locker room almost immediately, moving under his own power but limping.
He then returned for the second half, but left again nearly midway through the third quarter for the final time as it was clear the ankle was bothering him.
At the time of his departure, Lowry had 18 points, six rebounds and six assists on 58.3 per cent shooting in 22 minutes.