The team announced that VanVleet, who has been dealing with a left hip injury, will be out for recovery purposes. The 27-year-old had 30 points, six rebounds and seven assists in the team's 106-102 loss to the Utah Jazz the previous evening.
Meanwhile, Chris Boucher (left knee sprain), Gary Trent Jr. (left leg contusion) and Paul Watson (left knee tendinitis) will remain sidelined.
OG Anunoby will also miss Sunday's game as he recovers from a left calf strain.
VanVleet is averaging 19.4 points, 6.2 assists and 1.7. steals on 39.1 per cent shooting from the field and 36.7 per cent from three.
The Raptors are hoping to keep their slim post-season hopes alive with just eight games remaining.
You can catch the game on Sportsnet or SN Now at 10 p.m. ET / 7 p.m. PT.