Devils coach Lindy Ruff confirmed Hughes' status to reporters on Tuesday.
Hughes, 20, has been sidelined since suffering a separated shoulder on Oct. 19 against the Seattle Kraken. Hughes had two goals and one assist for three points through the first two games of the season.
The Devils are 9-6-4 this season. They are coming off a 5-2 win over the Philadelphia Flyers, just their second win in their last seven games (2-3-2).