Crosby was placed on the list on March 2 and missed the Penguins' game against the Philadelphia Flyers, a 5-2 Pittsburgh win, as a result.
A player's inclusion on the list does not necessarily mean they have tested positive for the novel coronavirus.
Penguins assistant coach Todd Reirden also passed COVID-19 protocols on Thursday, clearing the way for his return to the bench tonight against the Flyers.
In 20 games this season, Crosby is tied for the team lead in all major scoring categories with seven goals and 11 assists.
Tonight's game between Pittsburgh and Philadelphia can be watched on Sportsnet 360, with coverage beginning at 7 p.m. ET.