Watch the Penguins face off against the Ducks starting at 10 p.m. ET on Sportsnet.
Malkin missed the first few months of the 2021-22 campaign recovering from off-season surgery on his right knee.
A four-time All-Star and 2012 Hart Trophy winner, Malkin has 424 goals and 680 assists in 940 games since being selected second overall by the Penguins in 2004.
Pittsburgh (20-9-5) is fourth in the Metropolitan Division and just had a 10-game winning streak snapped with a 3-2 loss Saturday against the Dallas Stars.