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| Belt | Title holder | Since | Top contender | ||
| Heavyweight | Randy Couture * | April 15, 2006 | Brock Lesnar | ||
| * Randy Couture is the heavyweight champion while Antonio Rodrigo Nogueira is the interim title holder, which he earned by beating Tim Sylvia on February 2, 2008 after Couture had resigned. Couture is back and will face Brock Lesnar for the heavyweight belt, with the winner expected to take on the winner of a December bout between Nogueira and Frank Mir in a bout that will be champion vs. champion. | |||||
| Light Heavyweight | Forrest Griffin | July 5, 2008 | Rashad Evans | ||
| Forrest Griffin defeated Quinton Jackson on July 5, 2008 at UFC 86 to capture the LHW belt. | |||||
| Middleweight | Anderson Silva | October 14, 2006 | Patrick Cote | ||
| Anderson Silva defeated Rich Franklin on October 14, 2006 at UFC 64 to capture the MW title. | |||||
| Welterweight | Georges St. Pierre | April 19, 2008 | B.J. Penn | ||
| Georges St. Pierre defeated Matt Serra on April 19, 2008 at UFC 83 to capture the WW belt. | |||||
| Lightweight | B.J. Penn | January 19, 2008 | Kenny Florian | ||
| B.J. Penn defeated Joe Stevenson on January 19, 2008 at UFC 80 to capture the LW belt, which was vacant at the time. Sean Sherk was previously stripped of the title on December 8, 2007 because of a positive steroid test following his July 7, 2007 fight. Penn defeated Sherk on May 24, 2008 in his first belt defence. | |||||
| The weight classes are as follows:
Lightweight (146-155 lb / 66-70 kg) | |||||
