Bills, Patriots headline favourites on Week 10 NFL odds

Was last week's loss a wake up call for the Buffalo Bills? Drew and Cam think the Bills will be a lock on the road against the new York Jets.

The Buffalo Bills will be looking to rebound from their worst offensive performance in two years when they visit the New York Jets on Sunday as heavy 13-point road favourites on the NFL odds for Week 10 at sportsbooks monitored by OddsShark.com.

The Bills struggled on both sides of the ball while dropping a 9-6 decision in Jacksonville last weekend. That extended their current straight-up losing streak on the road to two games going into Sunday afternoon's matchup at MetLife Stadium.

The Bills have also gone winless against the spread in three straight outings, but maintain a narrow lead atop the AFC East over the New England Patriots. Buffalo's recent woes have failed to shake its position on the Super Bowl odds, however, as they continue to sit just behind the Tampa Bay Buccaneers (+600) as a +650 wager.

The Jets, meanwhile, return home looking for a third straight home victory. New York dropped a 45-30 decision in Indianapolis last week, but has averaged 30.5 points per game in consecutive home wins over Tennessee and Cincinnati.

Elsewhere this week, the New England Patriots will be looking to close the gap on Buffalo in the division standings with a fourth straight win as they battle the Cleveland Browns as slim 1.5-point home favourites at online sports betting sites. The Patriots established their longest win streak since October 2019 with last weekend's 24-6 rout of the Carolina Panthers, and now sit just a half-game back of the Bills in the AFC East. However, New England has struggled to produce as a home favourite, going 2-4 SU and ATS in its past six such outings.

The Browns travel to Gillette Stadium aiming to build on last week's 41-16 victory over the Cincinnati Bengals. That win snapped a shaky 1-3 SU and ATS run for Cleveland. However, the Browns face a huge challenge to flip the script after falling to defeat in six straight trips to New England since 1992.

Also, on the Week 10 NFL odds, both Aaron Rodgers and Russell Wilson could return to action when the Green Bay Packers host the Seattle Seahawks as 3.5-point chalk. Wilson has been sidelined by a finger injury suffered in Seattle's 26-17 loss to the Los Angeles Rams in Week 5, but has reportedly been given medical clearance. Rodgers missed the Packers' 13-7 loss in Kansas City after testing positive for COVID-19, but is looking increasingly likely to get the green light to return on Sunday.

As well, the Chiefs vie for a third straight win as they battle the Las Vegas Raiders on Sunday night as 2.5-point road favourites, while the Rams look for a fifth straight road win when they visit the San Francisco 49ers on Monday night as 4-point betting favourites.

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