The Arizona Cardinals will be looking to remain the only undefeated team in the NFL this season when they host the San Francisco 49ers on Sunday afternoon as 5.5-point favourites on the NFL odds for Week 5 at sportsbooks monitored by OddsShark.com.
Arizona is coming off a lopsided 37-20 road win over the Los Angeles Rams to improve its straight-up record to 4-0 going into Sunday afternoon’s matchup at State Farm Stadium.
The Cardinals have emerged as the highest scoring team in the NFL while enjoying their fastest start since 2012. Arizona has averaged an impressive 35 points per game during its season-opening win streak, claiming victory by double-digit margins on three occasions during that stretch. However, it was the Cardinals’ lone home contest that proved to be their narrowest victory, a come-from-behind 34-33 win over the Minnesota Vikings back in Week 2.
The Cardinals have compiled a middling 4-4 SU record in their past eight home dates while going 2-6 ATS, according to the OddsShark NFL Database. They are also 1-4 ATS in their past five games at home while favoured by more than three points, losing outright in three of those outings. Those recent trends have not helped to boost the odds of Arizona going undefeated this season, which lag at a lengthy +10000 at online betting sites.
The Niners travel to the desert looking for answers after dropping their second straight home contest, a 28-21 loss to the rival Seattle Seahawks. San Francisco has enjoyed recent success on the road, opening the season with wins in Detroit and Philadelphia. That extends to recent trips to Arizona, where they have won two straight, capped by a 20-12 victory as six-point underdogs in Week 16 of last season.
Elsewhere on the Week 5 NFL odds, the winless Jacksonville Jaguars will try to tune out the off-field controversy engulfing head coach Urban Meyer as they host the slumping Tennessee Titans as four-point underdogs. The Jaguars should be well-rested after dropping a 24-21 decision in Cincinnati last Thursday night that extended their current SU losing streak to 19 games, including an 0-9 SU and 2-7 ATS run at home.
The Titans look to rebound after last weekend’s stunning 27-24 loss to the New York Jets, and have limited the Jaguars to just 13 points per game during a 3-1 SU and ATS stretch at TIAA Bank Field.
As well, the Lions also search for their first victory of the season as they visit Minnesota as 7.5-point underdogs on Sunday afternoon, while Sunday Night Football features a potential AFC Championship Game preview as the Kansas City Chiefs host the Buffalo Bills as three-point chalk.
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