Michael Hutchinson will act as Toronto's backup goalie in Campbell's absence, while Joseph Woll is moving to the team's taxi squad as a result of the injury.
It is not yet clear how Campbell was injured. The 29-year-old started in net for the Maple Leafs on Sunday when they took on the Calgary Flames. Near the end of the third period, Campbell appeared to be in discomfort after making a save and was seen hunched over in the crease and shaking his leg while the action was out of the Leafs' zone.
With less than a minute left in the game, a crease scramble led to Flames forward Matthew Tkachuk's knee driving onto Campbell while he was lying face-down on the ice. Afterwards, it took a few moments for Campbell to get back on his feet, however he did stay in net for the remainder of the game.
Campbell did not practice with the Leafs on Monday. So far this season, Campbell is sporting a 2-0-0 record with a 2.00 goals-against average and a .923 save percentage.
Defenceman Travis Dermott will be a healthy scratch against Calgary Tuesday as Mikko Lehtonen will take his spot in the third pairing. It's the first time Dermott will be a healthy scratch since the 2018-19 season.