Acquired by the Leafs ahead of the NHL trade deadline, Foligno joined the team in Winnipeg after completing his seven-day quarantine at his home in Sudbury, Ont. The 33-year-old was skating on the Leafs' top line with Auston Matthews and Mitch Marner at practice.
The former Blue Jackets captain was traded to Toronto on April 11 for a first-round pick in the 2021 NHL draft and a fourth-round selection in 2022.
Keefe also said that Ilya Mikheyev will be a game-time decision after missing Tuesday's game against the Vancouver Canucks with an undisclosed injury.
Jack Campbell will get the start in goal as the Leafs take on the Jets on a Thursday edition of Wednesday Night Hockey on Sportsnet with puck drop set for 7:00 p.m. ET/8:00 p.m. CT.